HYBRID EVENT: You can participate in person at Rome, Italy or Virtually from your home or work.

2nd Edition of International Conference

and Expo on Clinical Microbiology

June 23-24, 2023 | Rome, Italy

ICCM 2022

Dimple Sethi Chopra

Speaker at Clinical Microbiology 2022 - Dimple Sethi Chopra
Punjabi University, India
Title : Multidrug resistance in burn patients


Staphylococcus and Pseudomonas spp. are the most common cause of infection in patients suffering burn injuries.As burn patients have lost their primary protective barrier ie skin, they are susceptible to colonization by both endogenous and exogenous micro-organisms. The thermal injury itself decreases host resistance and increases the body’s natural inflammatory response. The burn eschar provides an environment conducive to bacterial growth because of its protein richness, release of toxic substances, and avascularity, which impedes the delivery of antimicrobial drugs. In the first five days, post-burn the most common pathogens are gram-positive, whereas gram negative bacteria increase in prevalence after five days. The most common pathogens in the early phase are Staphylococcus aureus, Haemophilus influenza, Escherichia coli, and Klebsiella.The most common late-phase pathogens include S. aureus and Pseudomonas aeruginosa. Yeast and fungal infections typically occur, around 7–14 days, post-burn, followed by multi-drug–resistant (MDR) infections.The crucial risk factors for Multidrug bacteria, include length of stay in hospital, previous antimicrobial therapy, inadequate burn excision, and use of invasive medical devices. Although, intravenous (IV) and intra-arterial catheters are used in burn patients to provide access for fluid resuscitation, parenteral nutrition, and administration of medications. But, they increase the risk of central line-associated blood stream infection (CLABSI). Diagnosis of MDR is difficult, as colonization usually precedes infection.Because of empiric treatment with broad-spectrum antibiotics during the initial burn treatment, resistance patterns and sensitivities vary. Pathogens of utmost concern are MDR strains of P. aeruginosa, Stenotrophomonas maltophilia, Acinetobacter, and methicillin-resistant S. aureus (MRSA). There also have been reports of outbreaks of carbapenem resistant Enterobacteriaceae in burn unit.  
What will audience learn from your presentation?  

  • Awareness about Multi Drug Resistance. 

  • Burn wounds are different from other wounds. Their healing mechanism is also different. 

  • Burn wound patients should be strictly prevented from secondary infection. 

  • Initial management of burn patients decides their length of stay in the hospital. 

  • Trained Paramedical staff to deal with Fire disasters are need of the hour. 


She is presently working as Associate Professor in Department of  Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala. Her areas of interest are Biopharmacokinetics, molecular nanotechnology, targeted drug delivery, nanobiotechnology and nanomedicine. She is a member of American Nano Society.  She is on editorial board of many international journals. She has been granted two Indian Patents on Brain Permeable Nanoparticles. She has published several research papers in national and international journals of repute. She is an invited manuscript reviewer of many international journals. Recently she has edited book published by IGI Global “Strategies to Overcome Superbug Invasion” DOI: 10.4018/978-1-7998-0307 https://www.igi-global.com/book/strategies-overcome-superbug-invasions/227624
SciProfiles ID 1450343 , ORCID 0000-0001-7220-5660