International Conference and Expo on

Clinical Microbiology

June 17-18, 2022 | Online Event

ICCM 2022

WGS based analysis of bovine mastitis-related MRSA in Thuringia, Germany

Speaker at Clinical Microbiology 2022 - Amira Awad Moawad
Federal Research Institute for Animal Health, Germany
Title : WGS based analysis of bovine mastitis-related MRSA in Thuringia, Germany

Abstract:

In animal husbandry, acute and chronic staphylococcal mastitis cause massive financial losses for the producer due to the reduced milk yield of the infected cow, price reductions due to reduced milk quality up to a ban on milk sales and significantly increased premature loss of animals. A multi-parametric staphylococcal rapid test is to be developed to match this one-health problem. The probability that a dairy cow will be culled increases significantly after three udder treatments. A major cause of these infections is Staphylococcus (S.) aureus. In the case of sanitation, the quarter milk samples from 10% of the animals in a herd (assumed infection rate of approx. 25%) with cell counts greater than 250,000 cells/mL milk must be examined, as well as dry cows, heifers and newcomers.
The aim of the study was to compare the genotypes, antimicrobial resistance profiles, and virulence factors of MRSA strains from clinical and subclinical bovine mastitis in dairy farms in Thuringia, Germany. Whole-genome sequencing (WGS) of strains was conducted and the sequence data were analyzed regarding antimicrobial resistance and virulence associated genes to draw conclusions for a current situation of bovine clinical and subclinical mastitis infections in dairy herds in the state and the potential public health risk. Furthermore, mapping the possible phylogenetic relations between MRSA strains from various farms as well as within one farm.

What will audience learn from your presentation?

  • Audience will expand their knowledge about current situation of bovine mastitis in Germany.
  • Audience will get a knowledge about the important resistance genes in bovine mastitis associated pathogens.
  • provide new information to assist in a study-design to solve mastitis problem in dairy herds.

Biography:

Dr. Amira Moawad is currently working as Ass. Professor at Animal Health Research Institute. She became from 2016 until now a scientific researcher at Friedrich-Loeffler-Institute. Her PhD was on different mechanisms of antimicrobial resistance in pathogens of human and animal origin. She practices research in Microbiology and Molecular Biology. Since 2017, she has cooperated in international Projects funded by German federal foreign Office. She is now working on a project to develop a rapid pen-side device for rapid diagnosis of mastitis direct in the dairy farms

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